发明名称 A composition comprising a dendritic polymer in complex with at least one unit of biological response modifier and a process for the preparation thereof
摘要 Dendritic polymer conjugates which are composed of at least one dendrimer in association with at least one unit of a carried material, where the carrier material can be a biological response modifier, have been prepared. The conjugate can also have a target director present, and when it is present then the carried material may be a bioactive agent. Preferred dendritic polymers are dense star polymers, which have been complexed with biological response modifiers. These conjugates and complexes have particularly advantageous properties due to their unique characteristics.
申请公布号 IL128775(D0) 申请公布日期 2000.01.31
申请号 IL19990128775 申请日期 1999.03.01
申请人 THE DOW CHEMICAL COMPANY.;DENDRITECH, INC.;THE REGENTS OF THE UNIVERSITY OF MICHIGAN. 发明人
分类号 C12N15/02;A01N25/10;A61K;A61K31/70;A61K38/00;A61K39/385;A61K39/44;A61K45/00;A61K47/34;A61K47/48;A61K48/00;A61K49/00;A61K51/00;C07C211/29;C07C233/11;C07C237/20;C07K;C07K14/525;C07K14/535;C07K14/54;C07K14/555;C07K17/06;C07K17/08;C08G73/00;C08G83/00;C08L101/00;C12N;C12N5/10;C12N15/09;C12N15/57;C12N15/87;C12P21/02;C12P21/08;C12R1/91;(IPC1-7):C07K 主分类号 C12N15/02
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