| 摘要 |
<p>Methods are provided for characterizing target polynucleotides on an array. The array is hybridized to probes, where the probes are fractionated and labeled with spectrally distinguishable labels in order to provide information about a physical attribute of the nucleic acid, e.g. length of mRNA, association with ribosomes, sub-cellular localization, etc. Nucleic acids present on the array are scored for hybridization with a probe having particular label characteristics. Based on this information, target nucleic acids are identified that correspond to the desired physical attribute.</p> |
