SYNTHETIC PEPTIDES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM FOR DIAGNOSIS AND TREATMENT OF ANTI-PHOSPHOLIPID SYNDROME
摘要
Synthetic peptides and derivatives thereof capable of inhibiting the biological activity of anti-beta-2-glycoprotein 1 ( beta 2GPI) monoclonal antibodies (mAbs) in vitro, and of inhibiting induction of experimental anti-phospholipid syndrome (APS) in mice by anti- beta 2GPI mAbs, are provided for the diagnosis and treatment of anti-phospholipid syndrome in humans.
申请公布号
WO0001729(A2)
申请公布日期
2000.01.13
申请号
WO1999IL00366
申请日期
1999.07.06
申请人
YEDA RESEARCH AND DEVELOPMENT CO. LTD.;BLANK, MIRI;CABILLY, SHMUEL;SHOENFELD, YEHUDA;KATCHALSKI-KATZIR, EPHRAIM