| 发明名称 |
NAALADASE INHIBITORS USEFUL AS PHARMACEUTICAL COMPOUNDS AND COMPOSITIONS |
| 摘要 |
The present invention relates to N-Acetylated alpha -Linked Acidic Dipeptidase (NAALADase) inhibitors enzyme activity, pharmaceutical compositions comprising such inhibitors, and methods of their use to inhibit NAALADase enzyme activity, thereby effecting neuronal activities, inhibiting angiogenesis, and treating glutamate abnormalities, compulsive disorders, prostate diseases, pain and diabetic neuropathy.
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| 申请公布号 |
WO0001668(A2) |
申请公布日期 |
2000.01.13 |
| 申请号 |
WO1999US15128 |
申请日期 |
1999.07.02 |
| 申请人 |
GUILFORD PHARMACEUTICALS INC. |
发明人 |
JACKSON, PAUL, F.;MACLIN, KEITH, M.;WANG, ERIC;SLUSHER, BARBARA, S.;LAPIDUS, RENA, S.;MAJER, PAVEL |
| 分类号 |
C07D213/55;A61K31/19;A61K31/192;A61K31/194;A61K31/4406;A61K31/4409;A61K31/4418;A61P9/00;A61P13/08;A61P25/00;A61P25/04;A61P25/16;A61P25/18;A61P25/28;A61P25/30;A61P35/00;A61P43/00;C07C309/17;C07C309/24;C07C317/44;C07C323/12;C07C323/52;C07C323/56;C07C327/06;C07C327/12;C07C327/18;C07C327/22;C07C327/36;C07C329/12;C07C333/04;C07C333/14;C07C333/20;(IPC1-7):C07C319/00 |
主分类号 |
C07D213/55 |
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