| 发明名称 |
HIGH-EFFICIENCY AAV HELPER FUNCTIONS |
| 摘要 |
The present invention provides methods and compositions for producing high titer preparations of recombinant AAV ("rAAV") virions. The compositions of the present invention include AAV helper function systems and host cells. The present invention also includes methods of using AAV helper function vectors that effect the production of only small amounts of the long forms of Rep protein, and rAAV virions produced by such methods.
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| 申请公布号 |
WO0000589(A1) |
申请公布日期 |
2000.01.06 |
| 申请号 |
WO1999US15159 |
申请日期 |
1999.06.30 |
| 申请人 |
AVIGEN, INC. |
发明人 |
NATSOULIS, GEORGE;COLOSI, PETER;KURTZMAN, GARY |
| 分类号 |
C07K14/015;C12N5/10;C12N7/04;C12N15/864;(IPC1-7):C12N5/06;C12N5/08;C12N7/01;C12N7/02;C12N15/00;C12N15/35;C12N15/86;C12P21/00 |
主分类号 |
C07K14/015 |
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