发明名称 |
Therapeutic compositions that produce an immune response by altering the antigen |
摘要 |
The invention concerns methods and compositions for stimulating a host's immune response, particularly for the treatment of cancer. The methods and compositions according to the invention use binding agents such as antibodies to generate an immune response to a predetermined soluble antigen. In accordance with the invention, the binding agent-soluble antigen complex alters the immunogenic condition of the host by generating new immunogens that are recognizable by the immune system. This leads to a humoral and/or cellular immune response. |
申请公布号 |
AU4159399(A) |
申请公布日期 |
2000.01.05 |
申请号 |
AU19990041593 |
申请日期 |
1999.06.15 |
申请人 |
ALTAREX CORP |
发明人 |
RAGUPATHY MADIYALAKAN;BIRGIT SCHULTES;RICHARD P BAUM;ANTOINE A NOUJAIM;BEATRICE LEVEUGLE;FERNANDO T. KREUTZ |
分类号 |
A61K45/00;A61K38/00;A61K39/00;A61K39/395;A61K41/00;A61P35/00;A61P37/02;A61P37/04;C07K16/30;C07K16/42 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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