Etylenglykolestere av monohydrobenzoporfyrin derivater som fotoaktive midler
摘要
Compounds of the formula <CHEM> <CHEM> or the metallated or labeled or conjugated form thereof wherein each R<1> is independently alkyl (1-6C); each n is independently an integer of 0-6; and R<2> is vinyl or a derivative thereof obtainable by addition or oxidation of the vinyl group; are useful in the manufacture of a photoactive compound for use in photodynamic therapy (PDT) in which the PDT is to treat tumour cells, or to modulate an immune response, to constrict or occlude vasculature or to modulate intracellular signalling.
申请公布号
NO995436(A)
申请公布日期
2000.01.04
申请号
NO19990005436
申请日期
1999.11.05
申请人
QLT PHOTOTHERAPEUTICS INC;THE UNIVERSITY OF BRITISH COLUMBIA
发明人
STERNBERG, ETHAN D.;DOLPHIN, DAVID;RICHTER, ANNA M.;LEVY, JULIA G.;HUNT, DAVID WILLIAM CAREY;JAIN, ASHOK;WATERFIELD, ELIZABETH