发明名称 |
Use of anhydrovinblastine |
摘要 |
The present invention is particularly directed to the use of a derivative of vinblastine, 3',4'-anhydrovinblastine (AHVB), which differs from vinblastine in that it possesses a double bond at the 3',4' position of the caranthine nucleus rather than the hydroxyl group that is present in the parent structure, as an antineoplastic agent in the therapeutic treatment of cancer. Specifically, the treatment of lymphoma with 3',4'-anhydrovinblastine is disclosed.
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申请公布号 |
US6011041(A) |
申请公布日期 |
2000.01.04 |
申请号 |
US19960690195 |
申请日期 |
1996.07.26 |
申请人 |
UNIVERSITY OF BRITISH COLUMBIA |
发明人 |
SCHMIDT, BRUCE;KUTNEY, JAMES;MAYER, LAWRENCE |
分类号 |
C07D519/04;(IPC1-7):A61K31/33;A61K43/42;A61K31/485 |
主分类号 |
C07D519/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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