VIBRIO VULNIFICUS MOLECULAR PROBES, ANTIBODIES, AND PROTEINS
摘要
The present invention is directed to oligonucleotides used as amplification primers and assay probes for specific and sensitive for virulent strains of V. vulnificus. The target sequence of the probes and primers according to present invention is a capsular polysaccharide (CPS) transport gene (wza) of V. vulnificus. These probes can detect wza DNA or RNA in an unknown sample suspected to have pathogenic strains of V. vulnificus including human, animal, or environmental samples. The invention is also directed to in vitro-expressed protein from the cloned wza for production of polyclonal or monoclonal antibody that is specific for the wza gene product and will detect the V. vulnificus Wza protein in a sample comprising unknown protein.
申请公布号
WO9966074(A1)
申请公布日期
1999.12.23
申请号
WO1998US25729
申请日期
1998.12.04
申请人
UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE;WRIGHT, ANITA, C.;POWELL, JAN, L.;MORRIS, J., GLENN, JR.
发明人
WRIGHT, ANITA, C.;POWELL, JAN, L.;MORRIS, J., GLENN, JR.