发明名称 NUTRITIONAL ASSESSMENT BY MEASURING MITOCHONDRIAL COMPLEX ACTIVITY
摘要 According to a first aspect of the invention, a method of detecting malnutrition in a mammal is provided. The method includes the steps of: (a) measuring the activity in the mammal of one or more complexes selected from the group consisting of Complex I, Complex II, and Complex III; and (b) determining if the level of activity is below the level of activity of the complexes in a normal control sample. According to a second aspect of the invention, the use of Complex I is disclosed for nutritional assessment of a mammal. According to a third aspect of the invention, the use of Complex II is disclosed for nutritional assessment of a mammal. According to a fourth aspect of the invention, the use of Complex III is disclosed for nutritional assessment of a mammal. According to a fifth aspect of the invention, a kit for nutritional assessment of a mammal is provided, comprising one or more reagents for measuring the activity in the mammal of one or more complexes selected from the group consisting of Complex I, Complex II, and Complex III.
申请公布号 WO9966064(A1) 申请公布日期 1999.12.23
申请号 WO1999CA00551 申请日期 1999.06.14
申请人 JEEJEEBHOY, KHURSHEED 发明人 JEEJEEBHOY, KHURSHEED
分类号 C07K14/80;C12Q1/00;G01N33/50 主分类号 C07K14/80
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