发明名称 |
Method of inhibiting fibrosis with pyridoxal benzoyl hydrazone and analogs thereof |
摘要 |
Methods of inhibiting fibrosis comprising administering certain pyridoxal benzoyl hydrazones or analogs thereof are disclosed. Preferred hydrazones are pyridoxal benzoyl hydrazone, 3-hydroxyisonicotinaldehyde benzoyl hydrazone and salicylaldehyde benzoyl hydrazone. The methods are useful in treating fibrosing disorders, including dermal fibrosing disorders, fibrosis of internal organs and fibrotic conditions of the eye.
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申请公布号 |
US6005009(A) |
申请公布日期 |
1999.12.21 |
申请号 |
US19970821063 |
申请日期 |
1997.03.19 |
申请人 |
DUKE UNIVERSITY |
发明人 |
MURAD, SAOOD;PINNELL, SHELDON R.;YANG, HUANSHU |
分类号 |
A61K31/4415;(IPC1-7):A61K31/44;A61K31/165 |
主分类号 |
A61K31/4415 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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