摘要 |
The disclosure describes new compositions of matter that are analogs of DNA and RNA containing heterocyclic bases that can form base pairs that fit the Watson-Crick geometry in that they involve a monocyclic six membered ring pairing with a fused bicyclic heterocyclic ring system composed of a five member ring fused with a six membered ring, with the orientation of the heterocycles with respect to each other and with respect to the backbone chain analogous to that found in DNA and RNA, but where these base pairs are joined by a pattern of hydrogen bonds different from that found in the AT and GC base pairs (a "non-standard base pair").
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