INDAN DERIVATIVES

摘要

Cardiac failure remedies containing as the active ingredient indan derivativ es represented by general formula (I) or medicinally acceptable salts thereof, wherein R1 is hydrogen, nitro, cyano, amino, C1-C6 alkylcarbonylamino or the like; R2 and R3 are each independently C1-C6 alkyl or the like; R4 is hydrox yl or C1-C6 alkylcarbonyloxy, or alternatively R4 together with R5 represents a bond or oxygen; R5 is hydrogen, or alternatively R5 together with R4 represents a bond or oxygen; R6 is hydrogen, hydroxyl, NR7R8 or the like; n is an integer of 0 to 4; X is C=O, CH2, SO2 or NR16; when X is C=O, CH2 or SO2, Y is NR17, while when X is NR16, Y is C=O; when Y is NR17, Z is absent, while when Y is C=O, Z is NR18; and W is aryl, a lactam ring or the like.