| 摘要 |
The present invention provides a cell implantation device comprised of a cell matrix system which is fixedly coupled to a flat sheet supporting structure, preferably ring-shaped. Cells are inoculated onto the matrix, which may be a cell supporting fiber or a hydrogel. The proliferation, viability, and functionality of the cells are characterized prior to encapsulation in an immunoisolatory semi-permeable membrane. Cell growth under controlled conditions allows the encapsulated device to provide a relatively constant dose of secreted protein. |
