| 摘要 |
The present invention relates to an agent for preventing and treating skin diseases comprising an ascorbic acid derivative, a composition containing the agent and a preparation containing the agent, each of which has an effect of preventing and/or treating skin diseases and is employable in various forms such as a medical product, a quasi-drug and a cosmetic material. An object of the present invention is to provide an agent, which causes neither irritation nor other side effects and is capable of effectively preventing and/or treating skin diseases, and a composition containing the agent. The agent for preventing and treating skin diseases according to the present invention comprises as an active ingredient an ascorbic acid derivative which is a compound represented by the following formula (1) or a salt thereof and which per se exhibits no anti-oxidation activity but is capable of transforming in vivo into a compound having an anti-oxidation activity; <CHEM> wherein R<1> represents a group capable of bonding to the carbon at the 2-position of the ascorbic acid skeleton through an ether or ester bond and transformable in vivo into a hydroxyl group, and R<2> to R<4> may be the same or different and each represents a hydroxyl group or a group derived therefrom. |
