发明名称 |
Cytochalasin and isoindolinone derivatives as inhibitors of angiogenesis |
摘要 |
The present invention relates to inhibition of angiogenesis and the treatment of diseases mediated by angiogenesis. Particularly, the invention relates to the inhibition of neovascularization and the treatment of cancer. The invention further relates to the use of cytochalasin derivatives for the inhibition of angiogenesis and the treatment of angiogenesis associated diseases. The invention also relates to new isoindolinone compounds, compositions containing them, and methods of inhibiting angiogenesis and treating angiogenesis associated diseases with the isoindolinone derivatives.
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申请公布号 |
US5994388(A) |
申请公布日期 |
1999.11.30 |
申请号 |
US19980042760 |
申请日期 |
1998.03.17 |
申请人 |
THE CHILDREN'S MEDICAL CENTER CORPORATION |
发明人 |
UDAGAWA, TATURO;D'AMATO, ROBERT J.;SHAH, JAMSHED H. |
分类号 |
A61K31/4035;A61K31/407;A61P35/00;C07D209/46;C07D491/04;C07D491/044;C07D491/153;(IPC1-7):A61K31/40;C07D209/58 |
主分类号 |
A61K31/4035 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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