发明名称 |
Stable highly active compositions of avidin with an inert support material (agar) a bulking agent and a protectant for separation |
摘要 |
Compositions and methods for avidin immobilized on an inert support material, e.g., agarose, are disclosed. The compositions have high activity levels of avidin and may further include a bulking agent, e.g., maltose, and a protectant to maintain the stability and integrity of the avidin agarose during lyophilization and terminal sterilization processes. These compositions have applicability in any instance wherein avidin, agarose and/or the avidin/biotin technology are useful. In particular, the present compositions are useful in an enzyme capture system to prepare fibrin monomer useful for fibrin sealants.
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申请公布号 |
NZ321820(A) |
申请公布日期 |
1999.11.29 |
申请号 |
NZ19960321820 |
申请日期 |
1996.10.28 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
BURTON, STEVEN J;PEARSON, JAMES C;EDWARDSON, PETER A D |
分类号 |
C12N11/10;A61L2/00;A61L24/10;C07K1/22;C07K14/36;C07K14/465;C07K14/75;C07K17/10;C12N11/16;C12P21/06;(IPC1-7):C12N11/02;G01N33/532 |
主分类号 |
C12N11/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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