发明名称 |
AMINO ACID MODIFIED POLYPEPTIDES |
摘要 |
Incorporation of certain amino acid analogs into polypeptides produced by cells which do not ordinarily provide polypeptides containing such amino acid analogs is accomplished by subjecting the cells to growth media containing such amino acid analogs. The degree of incorporation can be regulated by adjusting the concentration of amino acid analogs in the media and/or by adjusting osmolality of the media. Such incorporation allows the chemical and physical characteristics of polypeptides to be altered and studied.
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申请公布号 |
CA2328423(A1) |
申请公布日期 |
1999.11.25 |
申请号 |
CA19982328423 |
申请日期 |
1998.05.20 |
申请人 |
UNITED STATES SURGICAL CORPORATION |
发明人 |
GRUSKIN, ELLIOTT A.;BUECHTER, DOUGLAS D.;ZHANG, GUANGHUI;CONNOLLY, KEVIN |
分类号 |
C12N15/09;C07K14/00;C07K14/51;C07K14/78;C12N1/00;C12N1/15;C12N1/19;C12N1/21;C12N5/00;C12N5/10;C12P21/02;(IPC1-7):C12N5/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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