发明名称 METHOD FOR ORTHOMETALATION OF A CARBOCYCLIC AROMATIC DERIVATIVE BEARING AT LEAST AN ELECTRON DONOR GROUP
摘要 <p>The invention concerns a method for orthometalation of a carbocyclic aromatic derivative bearing at least an electron donor group, characterised in that it consists in reacting said carbocyclic aromatic derivative with an efficient amount of at least one alkaline metal in the presence of a compound of formula (I): RX, wherein: R represents a hydrocarbon radical having 1 to 20 carbon atoms which can be a saturated or unsaturated, linear or branched, acyclic aliphatic radical; a saturated or unsaturated, monocyclic or polycyclic cycloaliphatic radical; a saturated or unsaturated, linear or branched aliphatic radical bearing a cyclic substituent; and X represents a bromine or chlorine atom.</p>
申请公布号 WO1999059941(A1) 申请公布日期 1999.11.25
申请号 FR1999001163 申请日期 1999.05.14
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