发明名称 THERAPEUTICS USING A BISPECIFIC ANTI-HLA CLASS II INVARIANT CHAIN X ANTI-PATHOGEN ANTIBODY
摘要 Multivalent, multispecific molecules having at least one specificity for a pathogen and at least one specificity for the HLA class II invariant chain (Ii) are administered to induce clearance of the pathogen. In addition to pathogens, clearance of therapeutic or diagnostic agents, autoantibodies, antigraft antibodies, and other undesirable compounds may be induced using the multivalent, multispecific molecules.
申请公布号 CA2328528(A1) 申请公布日期 1999.11.25
申请号 CA19992328528 申请日期 1999.05.19
申请人 IMMUNOMEDICS, INC. 发明人 HANSEN, HANS
分类号 C12N15/09;A61K38/00;A61K39/395;A61K47/48;A61K51/10;A61P31/04;A61P31/10;A61P31/12;A61P31/18;A61P35/00;A61P37/02;A61P37/06;C07K16/08;C07K16/10;C07K16/12;C07K16/14;C07K16/18;C07K16/24;C07K16/28;C07K16/30;C07K16/42;C07K16/46;C12P21/08;(IPC1-7):A61K39/395;A61K39/40;A61K39/42 主分类号 C12N15/09
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