发明名称 LIPID COMPOUND DERIVED FROM SPHINGOID BASE AND ITS PRODUCTION AND ITS USE IN COSMETIC AND SKIN PREPARATION
摘要 PROBLEM TO BE SOLVED: To obtain a new lipid compound capable of recovering the flexibility of skins, and the gloss and pliability of hairs, and useful for cosmetics, etc. SOLUTION: This compound corresponds to a compound corresponding to formula I (R1 is a 1-31C, preferably 9-25C, hydrocarbon-containing group; OR2 is cholesteryl) in a pure form or in an isomer mixture form. For example, N-(cholesteryloxycarbonyl)-2-aminooctadecane-1,3-diol. The compound of formula I is obtained by reacting the amine functional group of a sphingoid base of formula II with s cholesteryl chloroformate of formula III in the presence of a base in a proper organic solvent. The compound of the formula I is preferably added to cosmetics or compositions for skins in amounts of 0.01-10 wt.%, respectively, to prepare the cosmetics or the compositions for the skins.
申请公布号 JPH11322785(A) 申请公布日期 1999.11.24
申请号 JP19990059746 申请日期 1999.03.08
申请人 L'OREAL SA 发明人 SEMERIA DIDIER;PHILIPPE MICHEL
分类号 A61K8/30;A61K8/00;A61K8/14;A61K8/34;A61K8/40;A61K8/41;A61K8/46;A61K8/68;A61K31/00;A61K36/736;A61P17/00;A61Q1/00;A61Q1/10;A61Q3/00;A61Q3/02;A61Q5/00;A61Q5/02;A61Q19/00;C07J9/00;C07J41/00;(IPC1-7):C07J9/00;A61K7/00;A61K7/032;A61K7/04;A61K7/06;A61K7/48 主分类号 A61K8/30
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