摘要 |
Novel intermediates, i.e., N-(2S-(2-propenyl)-octanoyl)-(1S)-(-)-2, 10-camphorsultam, N-(2S-(2-propynyl)octanoyl)-(1S)-(-)-2, 10-camphorsultam and N-(2R-(2-propyl)octanoyl)-(1S)-(-)-2, 10-camphor-sultam; processes for the preparation of the intermediates; and processes for the preparation of optically active 2S-(2-propenyl)octanoic acid, 2S-(2-propynyl)octanoic acid and 2R-propyloctanoic acid by using the same. Optically active 2R-propyloctanoic acid equivalent or superior to that prepared by the process of the prior art in optical purity can be efficiently prepared in shorter reaction steps.
|