发明名称 NOVEL INTERMEDIATES AND PROCESSES FOR THE PREPARATION OF OPTICALLY ACTIVE OCTANOIC ACID DERIVATIVES
摘要 Novel intermediates, i.e., N-(2S-(2-propenyl)-octanoyl)-(1S)-(-)-2, 10-camphorsultam, N-(2S-(2-propynyl)octanoyl)-(1S)-(-)-2, 10-camphorsultam and N-(2R-(2-propyl)octanoyl)-(1S)-(-)-2, 10-camphor-sultam; processes for the preparation of the intermediates; and processes for the preparation of optically active 2S-(2-propenyl)octanoic acid, 2S-(2-propynyl)octanoic acid and 2R-propyloctanoic acid by using the same. Optically active 2R-propyloctanoic acid equivalent or superior to that prepared by the process of the prior art in optical purity can be efficiently prepared in shorter reaction steps.
申请公布号 WO9958513(A1) 申请公布日期 1999.11.18
申请号 WO1999JP02427 申请日期 1999.05.11
申请人 ONO PHARMACEUTICAL CO., LTD.;YAMAMOTO, HISASHI 发明人 YAMAMOTO, HISASHI
分类号 C07C51/06;C07C51/36;C07D275/06;(IPC1-7):C07D275/06;C07C53/126 主分类号 C07C51/06
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