发明名称 |
NOVEL SUBSTITUTED ARYL HYDROXAMIC ACIDS AS METALLOPROTEINASE INHIBITORS |
摘要 |
The present application describes novel substituted aryl hydroxamic acids of formula (I) or pharmaceutically acceptable salt forms thereof, wherein ring A is a 5-8 membered ring containing from 0-1 additional heteroatoms selected from N, O, and S, which are useful as metalloproteinase inhibitors and inhibitors of TNF.
|
申请公布号 |
WO9958531(A1) |
申请公布日期 |
1999.11.18 |
申请号 |
WO1999US10357 |
申请日期 |
1999.05.12 |
申请人 |
DU PONT PHARMACEUTICALS COMPANY |
发明人 |
VOSS, MATTHEW, E.;DECICCO, CARL, P.;WEXLER, RUTH, R. |
分类号 |
C07D215/48;A61K31/16;A61K31/40;A61K31/401;A61K31/403;A61K31/404;A61K31/4365;A61K31/437;A61K31/4427;A61K31/4439;A61K31/444;A61K31/445;A61K31/4545;A61K31/47;A61K31/4709;A61K31/472;A61K31/4725;A61K31/495;A61K31/496;A61K31/5375;A61K31/5377;A61K31/54;A61K31/541;A61K31/554;A61P1/02;A61P1/04;A61P7/02;A61P7/04;A61P9/00;A61P9/02;A61P17/06;A61P19/02;A61P25/00;A61P27/02;A61P29/00;A61P31/00;A61P31/18;A61P35/04;A61P37/06;A61P43/00;C07D207/16;C07D209/42;C07D211/96;C07D217/22;C07D241/04;C07D265/30;C07D279/12;C07D281/06;C07D401/12;C07D413/12;C07D417/12;C07D471/04;C07D491/048;C07D495/04;C07D498/04;(IPC1-7):C07D417/12 |
主分类号 |
C07D215/48 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|