发明名称 |
Method for removal of residual organic solvents and use thereof in manufacturing pharmaceuticals |
摘要 |
A method for removing residual organic solvents from a bulk substance, for example from a pharmaceutical drug substance, comprises drying the bulk substance in the presence of water vapor, such that the residual organic solvent molecules are displaced with water vapor molecules.
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申请公布号 |
US5981751(A) |
申请公布日期 |
1999.11.09 |
申请号 |
US19980138086 |
申请日期 |
1998.08.21 |
申请人 |
JOHNSON MATTHEY PUBLIC LIMITED COMPANY |
发明人 |
MUDRYK, BOGDAN;DUNG, JEN-SEN;SAPINO, CHESTER;GURO, JAMES |
分类号 |
A61K9/00;A61K31/485;B01D3/10;C07B63/00;F26B3/00;F26B5/00;(IPC1-7):C07D489/00;C07D489/06 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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