发明名称 |
CONVERSION OF A HYDROXY GROUP IN CERTAIN ALCOHOLS INTO A FLUOROSULFONATE ESTER OR A TRIFLUOROMETHYLSULFONATE ESTER |
摘要 |
The present invention provides a method of converting a hydroxy group in alcohols containing an electron withdrawing group into perfluoroalkanesulphonate and fluorosulphonate esters, which are good leaving groups, with inversion of configuration where the hydroxyl-bearing carbon is chiral. The method consists of converting said alcohol to an O-N,N-dialkylsulphamate ester and reacting said O-N,N-dialkylsulphamate ester with a perfluoroalkanesulphonic acid or fluorosulphonic acid. Such a method is useful for preparing chiral compounds for pharmaceutical and agrochemical use.
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申请公布号 |
CA2330467(A1) |
申请公布日期 |
1999.11.04 |
申请号 |
CA19992330467 |
申请日期 |
1999.03.24 |
申请人 |
LOEWENTHAL, HANS JACOB;LOEWENTHAL, RON BENJAMIN |
发明人 |
LOEWENTHAL, HANS JACOB;LOEWENTHAL, RON BENJAMIN |
分类号 |
C07C303/24;C07C303/26;C07C303/34;C07C307/02;C07C309/65;C07C309/84;(IPC1-7):C07C303/34 |
主分类号 |
C07C303/24 |
代理机构 |
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主权项 |
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地址 |
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