发明名称 RADICICOL DERIVATIVES
摘要 Compounds represented by general formula (I) which show a tyrosine kinase inhibitory activity or salts thereof, wherein R<1> and R<2> represent each hydrogen, alkanoyl, etc.; Y represents optionally substituted alkylene; R<3> represents NR<5>R<6> (wherein R<5> represents hydrogen, optionally substituted lower alkyl, etc.; and R<6> represents substituted alkyl, etc.), NR<7>COR<8> [wherein R<7> represents hydrogen, optionally substituted alkyl, etc.; and R<8> represents substituted lower alkyl, substituted lower alkoxy, NR<9>R<10> (wherein R<9> and R<10> represent each hydrogen, optionally substituted lower alkyl, etc.)], NR<11>COR<12> (wherein R<11> represents optionally substituted lower alkyl, etc.; and R<12> represents lower alkyl, lower alkoxy, etc.), substituted lower alkoxy, optionally substituted alkenyloxy, etc.; X represents halogeno or forms together with R<4> a single bond; and R<4> forms together with X a single bond or represents hydrogen, alkanoyl, etc.
申请公布号 WO9955689(A1) 申请公布日期 1999.11.04
申请号 WO1999JP02138 申请日期 1999.04.22
申请人 KYOWA HAKKO KOGYO CO., LTD.;INO, YOJI;AMISHIRO, NOBUYOSHI;MIYATA, MAYUMI;AGATSUMA, TSUTOMU;MURAKATA, CHIKARA;AKINAGA, SHIRO;SOGA, SHIRO;SHIOTSU, YUKIMASA 发明人 INO, YOJI;AMISHIRO, NOBUYOSHI;MIYATA, MAYUMI;AGATSUMA, TSUTOMU;MURAKATA, CHIKARA;AKINAGA, SHIRO;SOGA, SHIRO;SHIOTSU, YUKIMASA
分类号 C07D313/00;(IPC1-7):C07D313/00;A61K31/335;A61K31/695;C07D493/04;C07F7/18 主分类号 C07D313/00
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