发明名称 CELL ADHESION INHIBITOR
摘要 PROBLEM TO BE SOLVED: To obtain a pharmaceutical composition useful as a cellular infiltration inhibitor based on cell adhesion inhibitory action, anti-inflammatory agent (e.g. antiallergic agent, antiasthmic agent), immunosuppressive agent or the like, by including a specific compound (salt) as active ingredient. SOLUTION: This pharmaceutical composition is obtained by including a compound (salt) of the formula [R<1> and R<2> are each OH or the like; R<3> is H, or R<1> and R<2> are bound to each other into OCH2 O; R<3> is H, or R<1> is H, and R<2> and R<3> are bound to each other into OCH2 O; R<4> is a lower alkyl or the like; R<5> and R<6> are each H, a lower alkyl or the like; R<7> and R<8> are each a lower alkoxy; R<9> is H, or R<7> and R<8> are bound to each other into COH2 O; R<9> is H, or R<7> is H, and R<8> and R<9> are bound to each other into OCH2 O; R<11> is a lower alkyl or the like; R<10> is COH2 O(=O)OCH3 or the like; R<12> is OH or the like, or R<10> and R<12> are bound to each other into CH2 CH2 , wherein a lower alkyl may be bond to X to which R<12> is bound; R<13> is H or the like; X is N or C, or the N involves a quaternary ammonium salt, X bears a counterion Y (Y is a halogen anion)].
申请公布号 JPH11302174(A) 申请公布日期 1999.11.02
申请号 JP19980113583 申请日期 1998.04.23
申请人 MARUHO CO LTD 发明人 KAMIMURA HIROMI;TAKASHIMA AYAKO;IWASAKI KATSUHIDE;MUKOYAMA YOHEI;KAMIGAICHI MIYOKO;TOUBETSUTO KENJI
分类号 C07D317/70;A61K31/357;A61K31/36;A61K31/435;A61K31/47;A61K36/18;A61P9/00;A61P9/10;A61P11/00;A61P29/00;A61P37/06;A61P37/08;A61P43/00;C07D455/03;C07D491/056;C07D491/153 主分类号 C07D317/70
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