发明名称 |
(in vivo) magnetic resonance vascular imaging using laser-polarized gas microbubbles |
摘要 |
Nuclear magnetic resonance (NMR) images of a human or animal subject's vascular system are enhanced by injecting a liquid comprised of a biocompatible liquid carrier and a dispersion of hyperpolarized gas microbubbles into the subject, followed by generating an image by NMR representing a spatial distribution of the hyperpolarized gas microbubbles injected into the human or animal subject's vascular system. Preferably, the hyperpolarized gas is Helium-3 and/or Xenon-129. The microbubbles most preferably have a mean diameter of less than about 35 mu m. |
申请公布号 |
AU3386799(A) |
申请公布日期 |
1999.11.01 |
申请号 |
AU19990033867 |
申请日期 |
1999.04.08 |
申请人 |
DUKE UNIVERSITY |
发明人 |
G. ALLAN JOHNSON;MARK S. CHAWLA |
分类号 |
A61K49/18;G01R33/28;G01R33/563 |
主分类号 |
A61K49/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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