摘要 |
<p>The present invention provides an engineered cell comprising a gene encoding a non-glucose insulin secretagogue receptor and an insulin gene, wherein at least one of said genes is a recombinant gene and the cell secretes insulin in response to glucose wherein at least one of said genes has been introduced into the cell by means of a recombinant vector. Also provided is a method for producing insulin, comprising: (a) culturing the cell of claim 1; (b) stimulating said cell to secrete insulin; and (c) collecting the secreted insulin.</p> |