| 摘要 |
This invention relates to 3-aryl-2-(1-substituted-4-piperidinyl)-1,1-dioxo-3H-benzo[d]isothiazoles and related compounds of the formula, where X and Y are independently halogen, loweralkyl, loweralkoxy, arylloweralkoxy, acyl, hydroxy, nitro, amino, trifluoromethyl and hydrogen; n, p and q are independently integers of 1 or 2; R is hydrogen, loweralkyl, aryloweralkyl, acyl, -(CH2)m-OR1,-(CH2)NHR1, where R1 is hydrogen, loweralkyl, arylloweralkyl, acyl and loweralkoxycarbonyl; Z is hydrogen, halogen, loweralkyl, loweralkoxy and acyl; m is an integer of 2 to 4; is an integer of 1 or 2; and the pharmaceutically acceptable acid addition salts thereof and the optical isomers thereof where such isomers exist.
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