| 摘要 |
A compound of formula (I): in which: R1 represents halogen or hydroxyl, alkoxy, trihalomethyl, amino, mercapto, alkylthio, trialkylammonium, aryloxy, arylthio, arylsulfonyl, arylsulfonyloxy, cycloalkyloxy, cycloalkylthio, bicycloalkyloxy or bicycloalkylthio, Ra and Rb, which may be identical or different, represent hydrogen or alkyl, X represents oxygen or sulfur or NR, Y represents the group as defined in the description, R2 represents an optionallly substituted aryl, its optical isomers as well as its addition salts with a pharmaceutically acceptable acid or base and medicinal products containing the same are useful as interleukin-1 beta inhibitor.
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