发明名称 |
Brain cell protective agent |
摘要 |
The present invention relates to a novel brain cell protective agent having for its active ingredient a morphinan derivative represented with Compound 1 or pharmacologically acceptable acid addition salt thereof. The compounds used in the present invention were found to have excellent defensive effects against brain nerve cell necrosis in both in vitro and in vivo pharmacological evaluations, and can be used as useful preventive and therapeutic agents of ischemic brain disorders, brain nerve cell disorders and dementia.
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申请公布号 |
US5972953(A) |
申请公布日期 |
1999.10.26 |
申请号 |
US19960745041 |
申请日期 |
1996.11.07 |
申请人 |
TORAY INDUSTRIES, LTD. |
发明人 |
NAGASE, HIROSHI;IMAMURA, YOSHIFUMI;ENDO, TAKASHI;MATSUDA, SUSUMU;MIYAUCHI, YASUSHI |
分类号 |
A61K31/485;C07D489/00;(IPC1-7):A61K31/485 |
主分类号 |
A61K31/485 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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