The present invention provides improved compositions for improving the chemical and physical stability of peptides and proteins. The invention provides a liquid beneficial agent formulation containing a liquid suspension comprising at least 5% by weight beneficial agent and having a viscosity and beneficial agent size which minimizes settling of the agent in suspension over the extended delivery period.
申请公布号
US5972370(A)
申请公布日期
1999.10.26
申请号
US19990238159
申请日期
1999.01.28
申请人
ALZA CORPORATION
发明人
ECKENHOFF JAMES B.;HOLLADAY, LESLIE A.;LEONARD, JR., JOHN JOSEPH;LEUNG, IRIS K. M.;TAO, SALLY A.;MAGRUDER, JUDY A.;CARR, JOHN P.;WRIGHT, JEREMY C.