METHOD FOR IN VIVO DETECTING TARGET PROTEIN GENE BY DRUG

摘要

A method for in vivo detecting a target protein gene by a drug, which comprises binding an antigenic substance to a drug to be administered to a living organism via a chemical crosslinker, using the obtained material as a probe, and directly screening the gene of the protein bonded to the above probe by using a cDNA expression library containing genes of the living organism to which the drug is to be administered. Compared with the conventional drug-fixed column methods, the above method makes it possible to directly and conveniently isolate the gene of the target molecule without resort to the purification of the protein and the analysis of the amino acid sequence thereof.