| 发明名称 |
DNA-targeted alkylating agents |
| 摘要 |
PCT No. PCT/AU95/00520 Sec. 371 Date Feb. 19, 1997 Sec. 102(e) Date Feb. 19, 1997 PCT Filed Aug. 23, 1995 PCT Pub. No. WO96/06831 PCT Pub. Date Mar. 7, 1996The invention relates to novel bis-benzimidazole compounds which have the ability to bind to the minor groove of DNA and to alkylate DNA, to methods of preparing the compounds, and the use of the compounds in the treatement of neoplastic disease.
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| 申请公布号 |
US5968933(A) |
申请公布日期 |
1999.10.19 |
| 申请号 |
US19970793135 |
申请日期 |
1997.02.19 |
| 申请人 |
AUCKLAND DIVISION CANCER SOCIETY OF NEW ZEALAND INC.;CIRCADIAN PHARMACEUTICALS (AUSTRALIA) PTY. LTD. |
发明人 |
DENNY, WILLIAM A.;SMAILL, JEFFREY B. |
| 分类号 |
C07D235/18;C07D403/06;C07D403/14;(IPC1-7):C07D235/14 |
主分类号 |
C07D235/18 |
| 代理机构 |
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| 主权项 |
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