| 摘要 |
PROBLEM TO BE SOLVED: To obtain an inflammation treating agent useful for a disease accompanying an inflammation generated at a joint such as chronic rheumatism by blending a hyaluronic acid and a water soluble anti-inflammatory agent to make a preparation and performing a sterilizing treatment. SOLUTION: This inflammation treating agent for local administration is obtained by blending (A) a hyaluronic acid having preferably 400,000-5,000,000 molecular weight or its salt (e.g. sodium hyaluronate) with (B) a water-soluble anti-inflammatory agent (a steroidal agent such as sodium dexamethasone phosphate and sodium betamethasone salicylate, and a non steroidal agent such as sodium salicylate) to make a preparation and then performing a sterclizing treatment by a filtering sterilizing method by using preferably a filter of 0.22μm or 0.45μm. Further, it is preferable to use the above component (A) by dissolving with water or a water soluble solvent to form >=0.5 w/v% concentration.
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