摘要 |
A non-invasive method for the measurement of intracellular sodium concentration using multiple quantum nuclear magnetic resonance (NMR) is disclosed. Unlike current methods, the present method does not use intervention or any chemical reagents. One example of multiple quantum NMR is TQF NMR. As an indicator of cell functioning, its viability the intracellular sodium can be used for diagnosis, and evaluating the efficiency of corresponding pharmaceutical interventions. Further, the method can be implemented for any tissue in both animals, and humans. Being completely non-invasive, the method has especially promising applications for brain study. |