发明名称 |
Identification of factors which mediate the interaction of heterotrimeric g proteins and monomeric g proteins |
摘要 |
Monomeric GTPase guanine nucleotide exchange factor (GEF) have been identified which also contain an RGS region analogous to those of GTPase activating proteins (GAP). One of these GEF proteins, a Rho GEF has been demonstrated to contain an RGS sequence that has GAP activity toward a alpha subunit of a heterotrimeric G prote in. |
申请公布号 |
AU3103899(A) |
申请公布日期 |
1999.10.11 |
申请号 |
AU19990031038 |
申请日期 |
1999.03.18 |
申请人 |
ONYX PHARMACEUTICALS, INC. |
发明人 |
GIDEON BOLLAG;MATTHEW J. HART;WILLIAM ROSCOE;PAUL POLAKIS;PAUL STERNWEIS;TOHRU KOZASA;XUEJUN JIANG |
分类号 |
C12N15/09;C07K14/00;C07K14/47;C07K14/82;C12N5/10;C12N9/16;C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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