Processes for improved presentation of antigens by dendritic cells

摘要

The invention relates to a process for preparing dendritic cells which present complexes of peptides and MHC molecules on their surface, by contacting the dendritic cells with bacteria that present a protein on their surfaces or in the cytosol, which include the sequences of the peptides. The bacteria are preferably transformed so that they produce a heterologous protein which is expressed on their surface.