| 摘要 |
PROBLEM TO BE SOLVED: To produce the subject compound useful as an intermediate for producing a synthetic antimicrobial agent according to a simpler method in a higher yield than those in a conventional method by reacting a specific carboxylic acid with propylene oxide in the presence of a specified metal complex catalyst. SOLUTION: A carboxylic acid represented by the formula: RCOOH (R is a 1-20C alkyl or the like) (e.g. benzoic acid or p-nitrobenzoic acid) is reacted with propylene oxide in the presence of a metal complex catalyst represented by the formula R<1> is a 1-20C alkylene or the like; X<1> to X<10> are each H, a halogen, an alkyl or the like; M is M<1> (M<1> is a bivalent metal atom or a bivalent metal ion), M<2> -A<1> (M<2> is a bivalent metal atom or a trivalent metal atom; A<1> is a ligand) or M<3> -A<2> (M<3> is a trivalent metal ion; A<1> is a counterion), preferably M<1> and especially preferably when M<1> is a bivalent cobalt atom [CoII]} to thereby afford the objective compound represented by the formula: CH3 CH (OH)CH2 OCOR. |
