BIORESORBABLE AND REOSSIFYING POORLY CRYSTALLINE HYDROXYAPATITE USEFUL AS A BONE SUBSTITUTE MATERIAL FOR THE TREATMENT OF BONE DISORDERS, INJURIES.

摘要

The present invention provides a process for converting a standard inert amorphous calcium phosphate precipitate into highly reactive amorphous solids. The amorphous solids can be used to react with other calcium phosphate solids to form a poorly-crystalline synthetic hydroxyapatite that provides both bioactivity and structural integrity. This novel amorphous material can be reacted with other calcium phosphates at or below 37 °C to form a bone-like material consisting of poorly cyrstalline hydroxyapatite.