发明名称 NK-1 receptor antagonists for the treatment of delayed emesis.
摘要 The use of a compound of the formula: - (2S,3 S)-3-(2-methoxy-5-trifluoromethoxybenzyl)amino-2-phenylpiperidine; (2S,3 S)-N-(5-tert-butyl-2-methoxyphenyl)methyl-2-diphenylmethyl-1-azabicycl o-Ä2.2.2Üoctan-3-amine; or (2S,3 S)-N-(5-isopropyl-2-methoxyphenyl)methyl-2-diphenylmethyl-1-azabicyclo -Ä2.2.2Üoctan-3-amine; or of a pharmaceutically acceptable salt of one of the foregoing compounds, for the manufacture of a medicament for preventing or treating delayed emesis in a mammal.
申请公布号 ZA9802603(B) 申请公布日期 1999.09.27
申请号 ZA19980002603 申请日期 1998.03.27
申请人 PFIZER INC. 发明人 ATSUSHI NAGAHISA;MEGUMI TSUCHIYA;SANDRA LETA SILBERMAN
分类号 C07D453/02;A61K31/00;A61K31/435;A61K31/439;A61K31/445;A61K31/451;A61K33/24;A61K45/00;A61P1/00;A61P1/08;A61P43/00 主分类号 C07D453/02
代理机构 代理人
主权项
地址