摘要 |
FIELD: organic chemistry. SUBSTANCE: invention relates to derivatives of aminostilbazole of the general formula (I) <EMI ID=0.535 HE=33 WI=60 TI=CHI> where R or R is hydrogen atom; R<SP>3</SP>,R - H, C<SB>1-6</SB>-alkyl or hydroxy-group; R<SP>4</SP>,R - H, C<SB>1-6</SB>-alkyl, C<SB>1-6</SB>-alkoxy-, hydroxy-group, halogen atom or R<SP>4</SP>,R can in common form methylenedihydroxy-group; R - H, C<SB>1-6</SB>-alkyl possibly substituted with halogen atom, amine, mono- or dialkylamino-, morpholino-, alkoxy- or hydroxy-group, C<SB>1-6</SB>-acyl; R - phenylsulfonyl possibly substituted with alkyl, alkoxy-, halogenalkoxy-, hydroxy-, nitro-group or halogen atom; A, B and G - CH, N, N-O, N<SP>+</SP>-(R<SP>7</SP>)E where R is C<SB>1-6</SB>-alkyl or benzyl; E - anion; Y and Z - a ring, or their hydrates or salts that show an anticancer effect. EFFECT: an anticancer effect of compounds. 6 cl, 4 tbl, 59 ex
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