发明名称 |
Expression system for clostridium species |
摘要 |
A system is used to express clostridial gene constructions in a clostridial host. A mobilizable transfer plasmid is described which permits the direct transfer of the plasmid, and genes carried on it, from E. coli into Clostridium species. A promoter is described for use in clostridial species. Also, a useful host strain is used which is nontoxigenic and which permits high levels of expression of clostridial genes using the clostridial promoter.
|
申请公布号 |
US5955368(A) |
申请公布日期 |
1999.09.21 |
申请号 |
US19980056075 |
申请日期 |
1998.04.06 |
申请人 |
WISCONSIN ALUMNI RESEARCH FOUNDATION |
发明人 |
JOHNSON, ERIC A.;BRADSHAW, MARITE;ROOD, JULIAN I.;LYRAS, DENA |
分类号 |
C07K14/33;C12N1/21;C12N15/74;(IPC1-7):C12N1/21;C12N15/70;C12N15/64 |
主分类号 |
C07K14/33 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|