发明名称 |
Protein tyrosine phosphatase |
摘要 |
A novel protein tyrosine phosphatase designated PTP-S31 and its subfamily are identified, as are nucleic acid molecule coding therefor. Included in this family are PTP-S31 proteins or glycoproteins having one, two, or three identified amino acid changes in previously defined consensus sequences in the catalytic phosphatase domains of known protein tyrosine phosphatases. The PTP-S31 proteins or glycoproteins may be produced by recombinant means. Antibodies to PTP-S31 proteins or glycoproteins and nucleic acid constructs coding therefor, and methods for screening molecules which can bind to PTP-S31 proteins or glycoproteins and inhibit or stimulate their enzymatic activity, are provided.
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申请公布号 |
US5952212(A) |
申请公布日期 |
1999.09.14 |
申请号 |
US19950449609 |
申请日期 |
1995.05.24 |
申请人 |
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. |
发明人 |
MOLLER, NIELS PETER HUNDAHL;MOLLER, KARIN BACH;ULLRICH, AXEL |
分类号 |
G01N33/53;A61K38/00;A61K38/46;A61K39/395;A61P43/00;C07K14/47;C07K16/40;C12N1/21;C12N9/16;C12N9/18;C12N15/09;C12N15/55;C12P21/08;C12Q1/42;C12Q1/68;C12R1/19;G01N33/573;(IPC1-7):C12N9/12 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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