发明名称 |
Tandem synthetic HIV-1 peptides |
摘要 |
Novel synthetic peptides are provided which are candidate vaccines against HIV-1 and which are useful in diagnostic application. The peptides comprise an amino acid sequence of a T-cell epitope of the gag protein of HIV-1, specifically p24E linked directly to an amino acid sequence of a B-cell epitope of the V3 loop protein of an HIV-1 isolate and containing the sequence GPGR, and/or the gp41 containing the sequence ELKDWA. Multimeric forms of the tandem synthetic peptides are provided.
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申请公布号 |
US5951986(A) |
申请公布日期 |
1999.09.14 |
申请号 |
US19950467881 |
申请日期 |
1995.06.06 |
申请人 |
CONNAUGHT LABORATORIES LIMITED |
发明人 |
SIA, CHARLES D. Y.;CHONG, PELE;KLEIN, MICHEL H. |
分类号 |
G01N33/53;A61K39/00;A61K39/21;A61P31/12;A61P31/18;C07K14/155;C07K14/16;C07K16/10;C12N15/09;C12N15/48;G01N33/569;(IPC1-7):A61K39/21;A61K39/12;A61K38/00;C07K5/00 |
主分类号 |
G01N33/53 |
代理机构 |
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地址 |
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