PROCESS FOR THE PREPARATION OF SPHINGOLIPIDS AND SPHINGOLIPID DERIVATIVES

摘要

The present invention provides a production method in which a sphingolipid or a sphingolipid derivative having a modified or substituted long chain fatty acid bonded to a sphingoid is specifically synthesized from a sphingolipid or the like, and a sphingolipid or a sphingolipid derivative obtained by the production method. It is characterized in a method for producing a sphingolipid or a sphingolipid derivative, which comprises the step of enzymatically reacting a sphingolipid with an aliphatic carboxylic acid or the like using an enzyme which can specifically hydrolyze an acid-amide bond between a sphingoid and a fatty acid in a sphingolipid or the like to obtain another sphingolipid or sphingolipid derivative having a different fatty acid chain.