| 发明名称 |
MODIFICATION OF CLOSTRIDIAL TOXINS FOR USE AS TRANSPORT PROTEINS |
| 摘要 |
<p>A chemical conjugate for treating a nerve cell related disorder is provided. The conjugate includes an active or inactive Clostridial toxin having specificity for a target nerve cell. The toxin is conjugated to a drug or other bioactive molecule without affecting the toxin's ability to enter the target nerve cell.</p> |
| 申请公布号 |
EP0760681(B1) |
申请公布日期 |
1999.09.01 |
| 申请号 |
EP19950921007 |
申请日期 |
1995.05.31 |
| 申请人 |
ALLERGAN, INC |
发明人 |
DOLLY, JAMES OLIVER;AOKI, KEI ROGER;WHEELER, LARRY ALLEN;GARST, MICHAEL ELWOOD |
| 分类号 |
A61K38/00;A61K47/48;C07K14/33;(IPC1-7):A61K47/48 |
主分类号 |
A61K38/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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