Peptide derived from cedar pollen allergens and uses thereof

摘要

Disclosed are peptides which essentially consist of T-cell epitope(s) of cedar pollen allergens, homologous peptides thereunto, and immunotherapeutic agents containing such peptides as an effective ingredient. These peptides do not substantially react with immunoglobulin E antibody specific to cedar pollen allergens, and significantly more activate T-cells specific to cedar pollen allergens than a negative control when assayed by the <3>H-thymidine uptake method. Thus, the agents can effectively treat and/or the prevent cedar pollinosis without fear of causing side effects when administered to mammals including human.