| 发明名称 |
Inhibitors of cholesterol esterase |
| 摘要 |
The present invention provides novel haloenol lactones that are effective as active site inhibitors of cholesterol esterase. By inhibiting cholesterol esterase the inhibitors of the present invention provide a new approach to the treatment of hypercholesterolemia through limiting the bioavailability of dietary cholesterol.
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| 申请公布号 |
US5942631(A) |
申请公布日期 |
1999.08.24 |
| 申请号 |
US19980060250 |
申请日期 |
1998.04.15 |
| 申请人 |
UNIVERSITY OF NEW MEXICO |
发明人 |
DECK, LORRAINE;VANDER JAGT, DAVID L. |
| 分类号 |
C07D307/83;A61K31/365;A61K31/366;A61P3/06;A61P9/10;A61P43/00;C07D307/33;C07D309/30;C07D309/38;C07D311/20;C07D311/74;C07D311/76;(IPC1-7):C07D309/38 |
主分类号 |
C07D307/83 |
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